diff --git a/python/requirements.txt b/python/requirements.txt
index 59ecee414e8..433b2194701 100644
--- a/python/requirements.txt
+++ b/python/requirements.txt
@@ -6,12 +6,9 @@ mach == 0.6.0
 mozdebug == 0.1
 mozinfo == 0.8
 mozlog == 3.6
-setuptools == 18.5
+setuptools == 39.0
 toml == 0.9.2
 
-# For pycparser 2.19 release bustage
-pycparser != 2.19
-
 # For Python linting
 flake8 == 2.4.1
 pep8 == 1.5.7