diff --git a/.gitignore b/.gitignore
index 33f08eb5aed..46ed53e46cb 100644
--- a/.gitignore
+++ b/.gitignore
@@ -58,5 +58,8 @@ Sessionx.vim
 # Layout debugger trace files
 layout_trace*
 
+# Package managers
+support/macos/Brewfile.lock.json
+
 # direnv
 .envrc
diff --git a/README.md b/README.md
index ad0dd738395..4484b76e55e 100644
--- a/README.md
+++ b/README.md
@@ -25,7 +25,7 @@ manually, try the [manual build setup][manual-build].
 - Install [Xcode](https://developer.apple.com/xcode/)
 - Install [Homebrew](https://brew.sh/)
 - Run `curl --proto '=https' --tlsv1.2 -sSf https://sh.rustup.rs | sh`
-- Run `pip install virtualenv`
+- Run `pip3 install virtualenv`
 - Run `./mach bootstrap`<br/>
   *Note: This will install the recommended version of GStreamer globally on your system.*
 
diff --git a/python/servo/platform/macos.py b/python/servo/platform/macos.py
index 1bcb88cab54..34f936a3f21 100644
--- a/python/servo/platform/macos.py
+++ b/python/servo/platform/macos.py
@@ -55,7 +55,19 @@ class MacOS(Base):
         return True
 
     def _platform_bootstrap(self, _force: bool) -> bool:
-        return self._platform_bootstrap_gstreamer(False)
+        installed_something = False
+        try:
+            brewfile = os.path.join(util.SERVO_ROOT, "support", "macos", "Brewfile")
+            output = subprocess.check_output(
+                ['brew', 'bundle', 'install', "--file", brewfile]
+            ).decode("utf-8")
+            print(output)
+            installed_something = "Installing" in output
+        except subprocess.CalledProcessError as e:
+            print("Could not run homebrew. Is it installed?")
+            raise e
+        installed_something |= self._platform_bootstrap_gstreamer(False)
+        return installed_something
 
     def _platform_bootstrap_gstreamer(self, force: bool) -> bool:
         if not force and self.is_gstreamer_installed(cross_compilation_target=None):
diff --git a/support/macos/Brewfile b/support/macos/Brewfile
new file mode 100644
index 00000000000..1b321f0a8a9
--- /dev/null
+++ b/support/macos/Brewfile
@@ -0,0 +1,2 @@
+brew "cmake"
+brew "pkg-config"